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Avascular necrosis; Bone infarction; Ischemic bone necrosis; AVN; Aseptic necrosis. All these words are suitable and used in the understanding of this disease.


The disease called Osteonecrosis is bone death caused by poor blood supply. It is most common in the hip and shoulder, but can affect other large joints such as the knee, elbow, wrist and ankle.

Aseptic necrosis is bone death caused from a disruption in the blood supply. It is most common in the hip, knee, and shoulder.

Avascular necrosis or Osteonecrosis is a painful bone condition that gets worse over time and can affect your mobility. It occurs when something cuts off blood flow to one of your bones. Causes include broken bones, dislocated hips, radiation therapy and alcohol misuse. Most people need surgery sometimes joint replacement to ease pain and improve mobility.
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Osteonecrosis often shows up when part of the bone does not receive blood and dies. Sometimes later, the bone can collapse. If osteonecrosis is left not treated, the joint deteriorates, and then lead to severe arthritis.

Osteonecrosis can be caused by disease or by severe trauma, such as a fracture or dislocation, that affects the blood supply to the bone. Osteonecrosis can also occur without trauma or disease. This is called idiopathic that mean it show-up suddenly without any known cause. We hereby list the following cases as possible causes of Bone infarction.

  • The use of oral or intravenous steroids.
  • Excessive use of alcohol.
  • Sickle cell disease.
  • The dislocation or fractures around a joint.
  • Clotting disorders.
  • HIV or taking HIV drugs.
  • Radiation therapy or chemotherapy
  • The gaucher disease (disease in which harmful substance build up in the certain organs and the bone).
  • Systemic lupus erythematosus (an autoimmune disease in which the body’s immune system mistakenly attacks healthy tissue such as the bone).
  • Legg-Calve-Perthes disease (childhood disease in which the thigh bone in the hip doesn’t get enough blood, which cause the death of the bone to)
  • Decompression sickness from a lot of deep sea diving. These are likely the main causes of Osteonecrosis.

When osteonecrosis occurs in the shoulder joint, it is usually due to long-term treatment with steroids, a history of trauma to the shoulder, or the person has sickle cell disease.


For the main time or a starting of Osteonecrosis, in the early phase you have no symptoms. But as bone damage worsens, you may start have the following signs such as:

  • A pain in the joint that may increase over time and becomes severe if the bone collapses.
  • Pains that appear even at rest.
  • The limited range of your motion.
  • Groin pain, especially when the hip joint is affected.
  • A limping, if the condition appears in your leg
  • Some difficulties with overhead movement, if the shoulder joint is affected.

These are some major signs or symptoms your perceive when attacked by Osteonecrosis. For more discovery, kindly slide to our site on www.afriquebio.com. Advanced osteonecrosis can lead to osteoarthritis and permanent decreased mobility. Severe cases may require joint replacement.

By Agent Ade